Recommended Solutions for the Determination of Bisphenol A (BPA) Content and Migration

China Education Equipment Procurement Network News: According to the announcement issued by the General Administration of Quality Supervision, Inspection and Quarantine, from June 1, 2011, the production of baby bottles will be monitored, and the production of bottles containing bisphenol A will be prohibited. This website recommends solutions for the determination of bisphenol A (BPA) content and migration from related content published by Shimadzu Corporation.

The details are as follows:

Bisphenol A (BPA) is one of the most widely used industrial compounds in the world, mainly used in the production of various polymer materials such as polycarbonate, epoxy resin, polysulfone resin, polyphenylene ether resin, unsaturated polyester resin, etc. . In the manufacturing process of plastic products, the addition of bisphenol A can make it colorless and transparent, durable, lightweight and outstanding impact resistance, especially to prevent acidic vegetables and fruits from eroding the metal container from the inside, so it is widely used in canning In the process of manufacturing food and beverage packaging, milk bottles, water bottles and hundreds of other daily necessities. It can be said that BPA is everywhere.

The world produces 27 million tons of BPA-containing plastics every year. BPA can cause endocrine disorders and threaten the health of fetuses and children. Obesity caused by cancer and metabolic disorders is also considered to be related to this. Very low doses of bisphenol A can also have an impact on health, especially for fetuses and newborns, whose "exogenous effects" may cause harm through mutations. Therefore, the safety issue of bisphenol A has become the focus of public attention.

The EU banned the production of baby bottles containing the chemical substance bisphenol A (BPA) from March 2, 2011. From June 1, 2011, China banned the production of polycarbonate baby bottles and other baby bottles containing bisphenol A; from September 1, 2011, the import and sale of polycarbonate baby bottles and other Baby bottles containing bisphenol A are recalled by the manufacturer or importer. With the announcement of relevant national policies and regulations and the announcement of the Ministry of Health of China, industries involving bisphenol A will carry out comprehensive testing services, especially commodity inspection, quality inspection, CDC, etc. and production enterprises will increase inspection efforts.

Recently, Shimadzu Corporation, which has long paid attention to product safety and is committed to ensuring product safety with comprehensive and advanced testing and comprehensive solutions, has launched the LCMS method to measure the total content of BPA in consumer products and the migration of BPA in children ’s drinking utensils, tableware and feeding utensils solution. Shimadzu LCMS-2020 was used to analyze the total content of BPA in consumer products and the migration of BPA in children's drinking utensils, tableware and feeding utensils. The results showed that the standard curve of bisphenol A in the concentration range of 0.01 ~ 0.5 mg / L was linear and the correlation coefficient was 0.9999; the total content of BPA in consumer products and the detection limit of BPA migration in children's drinking utensils, tableware and feeding utensils The average recovery rates of the three spiked concentrations of 1.0 mg / kg and 0.01 mg / kg, 0.02, 0.05, and 0.1 mg / L were 93% and 92%, respectively, and the method had good reproducibility. For more information, please click to download the latest application data set: "Determination of Bisphenol A Content and Migration". Shimadzu LCMS-2020 uses a uniquely designed ion source and ion optical system, with ultra-fast scanning, high-speed positive and negative polarity switching function, to achieve high sensitivity and high stability. Operation and maintenance are simple and convenient. It also has a unique multi-sequence measurement method, which can measure data under a variety of analysis conditions in one injection, which greatly improves the analysis efficiency. In addition to LCMS-2020, Shimadzu's LC-20A and LCMS-8030 can be used to analyze the bisphenol A project.

[Reference: Bisphenol A related regulations and policies]

1. Norway: The earliest inclusion of bisphenol A in restricted substances should be the Norwegian PoHS directive that was originally scheduled to take effect on January 1, 2008, and was postponed because of many issues that have not yet reached consensus. Among the 10 substances used are bisphenol A (BPA).

2. Canada: On October 18, 2008, Canada declared bisphenol A as a toxic chemical substance, thus becoming the first country in the world to list bisphenol A as a toxic chemical substance, and banned the production process of baby bottles Use bisphenol A.

3. United States

1) Federal: The proposal in March 2009 prohibits the use of "Reusable Food Containers" and "Other Food Containers" (BPA). The ban took effect 180 days after it was officially adopted.

2). Suffolk County, New York: The resolution announced on April 2, 2009 will take effect 90 days later. Under this law, no one in Suffolk County may sell or provide for sale baby bottles and children's beverage containers containing BPA for children under 3 years of age.

3). Illinois: From July 1, 2010, no one shall sell, provide, distribute or provide sports water bottles containing bisphenol A for distribution, or children's food containers suitable for children 3 years of age or younger , Regardless of whether the container contains food or drink.

4). Maryland: stipulates that child care products must not contain bisphenol A or any other substances that are carcinogenic or toxic to the reproductive system, and the manufacturer must mark the product as free of bisphenol A. Violation of the above regulations can be fined up to US $ 10,000 each.

4. The new EU Regulation (EU) No. 10/2011 on food contact plastics and plastic products prohibits the production of plastic bottles containing bisphenol A from March 1, 2011, and prohibits the import of any bisphenol A plastic bottles from June to 2011. Member States.

5. In March 2009, China set a limit standard for the migration of bisphenol A in food contact materials (GB / T 23296.16-2009), which stipulates that the lower limit of determination of bisphenol A in water-based food simulants is 0.3 mg / L.

6. The EU 2002/72 / EC regulations stipulate that the migration limit of bisphenol A in plastic food contact materials is 3 mg / kg. The EU uses liquid chromatography to detect the migration of bisphenol A (detection limit is 0.2 ~ 0.7 mg / kg).

7. The US Food and Drug Administration (FDA) stipulates that bisphenol A can be used as a raw material for food contact materials. EPA (1993) stipulates that the maximum acceptable dose or reference dose is 0.05 mg / kg bw / day.

8. Japan's "Food Sanitation Law" stipulates that the dissolution limit of bisphenol A in polycarbonate food containers is 2.5 mg / kg.

9. The Ministry of Health of China and other six departments issued a joint announcement on May 30, 2011. From June 1, the production of polycarbonate baby bottles and other baby bottles containing bisphenol A is prohibited. As of September 1, 2011, the import and sale of polycarbonate baby bottles and other baby bottles containing bisphenol A are prohibited, and recalled by the manufacturer or importer.

About Shimadzu

Shimadzu International Trading (Shanghai) Co., Ltd. is a local legal person company established in China in 1999 by Shimadzu Corporation to expand the scale of its business in China.

At present, Shimadzu International Trading (Shanghai) Co., Ltd. has 12 branches throughout China, and its business scale is continuously expanding. There are analysis centers in Beijing, Shanghai, and Guangzhou; a network of sales agents covering 30 provinces across the country; and more than 60 technical service stations to build a complete system for providing good services to users.

As a global production base, Shimadzu has built a product production and supply system not only for Chinese customers, but also for the world, and strives to build a product production system that meets the requirements of the Chinese market. With the goal of "for the health of mankind and the earth", Shimadzu will always strive to provide users with more advanced products and more satisfactory services.

For more information, please visit Shimadzu's website.

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